Diagnostic Accuracy

Research Methods

Measures of Diagnostic Accuracy

Sensitivity: the ability of a test to correctly classify an individual as having a disorder

True Positive

True Positive + False Negative

Specificity: the ability of a test to correctly identify a person as not having a disorder

True Negative

True Negative + False Positive

Positive predictive value (PPV): the probability that an individual has a disorder given a positive test result

True Positive

True Positive + False Positive

Negative predictive value (NPV): the probability that an individual does not have a disorder given a negative test result

True Negative

True Negative + False Negative

Likelihood ratio positive (LR+): the confidence that a positive score on a test came from a person who has the disorder rather than from a person who does not have the disorder sensitivity / (1 – specificity)

Likelihood ratio negative (LR-): the confidence that a negative score on a test came from a person who does not have the disorder rather than from a person who has the disorder (1 – sensitivity) / specificity

Diagnostic odds ratio (DOR): a means of comparing tests by putting results on the same scale (think effect size), the higher the DOR the better the test is at identifying the true status of individuals who have and do not have the disorder LR+/LR

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